The benefits of nicotinamide riboside upon cognition and sleep in older Veterans
The University at Buffalo (UB) School of Nursing is looking for veterans aged 65 to 85 years old who have trouble sleeping for a 3-month study. The goal of this study is to see if vitamin B3 may help adults sleep better, which may help to improve thinking and memory.
Eligible participants will complete 4 study visits at the Buffalo VA (VA WNY Healthcare System, 3495 Bailey Avenue, Buffalo, New York 14215). They will complete surveys on sleep and memory, a blood draw at Visits 1 and 4, and wear a Fitbit (a watch that collects information on how many steps you take and your sleep). Participants will either take vitamin B3 or a placebo (which looks like the vitamin B3 pill but is a sugar pill) twice daily for 3 months. Participants will get to keep their Fitbit (a $149 value) and have complimentary parking for all study visits.
Poor sleep quality and short sleep duration may be a mechanistic component of cognitive impairment in older adults, associated with a decline in brain-derived neurotrophic factor. Increasing the availability of nicotinamide adenine dinucleotide (NAD+) with supplementation of its precursor, nicotinamide riboside (NR), a form of vitamin B3 may increase the expression of brain-derived neurotrophic fa
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Adults aged 65-85 years old
Have trouble sleeping
Have not been diagnosed with dementia
Fluent in English
Age Group: Adults
CARLEARA FERREIRA DA ROSA SILVA
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