This study enrolls children who are admitted to the pediatric intensive care unit. The purpose of this study is to learn about the effects of blood transfusion on multiple organ dysfunction syndrome (MODS). Patient’s participation in this study will involve giving blood and urine samples and chest x-rays. During the study, we will store and analyze participant’s blood and urine to measure certain protein levels and collect information about their genetic material (DNA). Compensation is not available for this study. Read More

Children ages 1 month to 18 years who are admitted to the pediatric intensive care unit.
Critically ill pediatric patients receiving blood transfusion who have an expected length of stay after transfusion in the ICU of more than 24 hours (based on the best judgment of the attending ICU staff).

This study is for people undergoing surgery for mitral regurgitation (MR). Mitral regurgitation is a condition when your heart’s mitral valve does not close tightly which causes blood to flow backwards in your heart. The purpose of this study is to learn how safe and effective one value repair system is (the PASCAL System, an investigational device) compared to another one (the MitraClip System). Read More

Adults ages 18+.
Have severe degenerative mitral regurgitation, and are considered prohibitive risk for mitral valve surgery by your heart team.

This study enrolls healthy adults. The purpose is to determine a standard for how healthy people walk so that we can better help patients who have difficulty walking. Read More

Healthy adults ages 20-80
English speaking
Able to walk without assistance.

The purpose of this study is to learn more about how nurse practitioner students and practicing nurse practitioners perceive the health needs Read More

Ages 18+
Understand and speak English
Have a state license as a nurse practitioner OR have a state license as a registered professional nurse while simultaneously seeking a nurse practitioner education
Have at least 3 months of professional practice in a setting that could potentially direct the care of adult lesbian, gay, bisexual, or transgender patients
Have nurse practitio...

This study enrolls healthy adults. The purpose of this study is to learn how people use memories and make decisions about their behavior. Read More

Healthy adults ages 18-64.
English spoken as first language.
USA residents.
Cannot be pregnant.

This study enrolls pharmacy students at the University at Buffalo. The purpose of this study is to design an integrative health elective for pharmacy students and evaluate their knowledge and perceptions before and after taking the elective. Read More

People ages 18+.
Students must be enrolled in the Integrative Health elective through UB's School of Pharmacy.

This study enrolls children ages 3-5 who attend certain Buffalo child care centers and their parents. This study is looking at early stressful experiences in the family and with friends at school. We are trying to find out how these experiences impact school readiness when children transition from preschool to kindergarten. We are also exploring how stressful experiences "get under the skin" and are measured in the stress hormone cortisol that we can measure in hair and saliva. Read More

Children ages 3-5.
Must be attending one of the participating child care centers in the larger Buffalo metro area.

This study enrolls currently practicing orthopaedic surgeons. The purpose of this study is to learn more about common practices in orthopaedic surgery. Read More

Adults ages 18+.
Currently Practicing Orthopaedic Surgeon.
Performs Joint Arthroplasty Procedures.

This study uses a phone app to track people’s life values and goals. It aims to help people improve their quality of life by completing their goals with the help of trained life coaches. It includes two in-person visits, a few phone check-ins, short tests, and questionnaires. Read More

60+ years old, Own smart phone, and Have no history of substance use problems or mental health/ neurological conditions.

This study is for people who read the Sofia Learns About Research book. The book is a coloring and activity book created to help children and families learn more about participating in research. Anyone can access the online, interactive version of the book and participate in the study. Read More

Children and adults (any age)
Have read or will read the Sofia Learns About Research Book

ALSO
Children in select classrooms in WNY where the Sofia Learns About Research book is being read.