We are looking for healthy adults age 21+  for a research study. The purpose of this study is to learn more about how bacteria in the mouth work.  We hope that with this understanding, new treatments can be designed to prevent disease. Read More

Age 21+.
In general good health.
Pregnant women may not participate.

This study enrolls babies with neonatal opioid withdrawal syndrome (NOWS). The purpose of this study is to learn about how babies with this syndrome grow and develop. This will help us learn the best way to care for babies with NOWS. Read More

Infants born at 36 weeks gestation or greater
Managed for NOWS at Oishei Children's Hospital

This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR) and have Heart Failure symptoms which are not under control despite treatment with current available therapies. The purpose of this study is to compare a new investigational (experimental) device plus optimal drug therapy with optimal drug therapy alone. Read More

Adults ages 18+
Diagnosed with moderate or greater Tricuspid Regurgitation/Insufficiency with Heart Failure symptoms

This study enrolls adults with head and neck cancer. The purpose of the study is to learn if a light device used in the mouth during chemotherapy and radiation can help prevent oral mucositis. Read More

Diagnosed with cancer (pathologically confirmed squamous cell carcinoma) of the oral cavity, oropharynx, tonsil or base of tongue.
Scheduled to have a continuous course of Intensity-Modulated Radiation Therapy (IMRT) over an estimated 6 to 8 weeks.

This study enrolls adults who have had a recent stroke or stroke symptoms. The purpose of this study is to compare how well the study drug (tenecteplase) works for people with stroke symptoms. Read More

-Adults ages 18+.
-Have been diagnosed with a stroke or stroke symptoms.
-Please contact the research team for other eligibility criteria.

This study enrolls people who have had a stroke in the past 2 weeks. This research is being done to figure out whether treatment for sleep apnea in people who have had a stroke or transient ischemic attack (TIA or "mini stroke"), improves recovery from stroke and helps prevent future stroke, heart problems, and death. Read More

Adults ages 18+.
Are at an inpatient at an enrolling site (Buffalo General Hospital or Gates Vascular Institute).
Have had an ischemic stroke or TIA within the past 14 days.
Use a CPAP machine.

This study enrolls newborns and their families. The purpose of this study is to learn more about newborn screening for immunodeficiency. Read More

Newborns and their families in New York State.