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Understanding and Treating Severe Gum Disease in Children and Teens
Protocol: STUDY00009798
Full Title
Mechanisms and Treatment Response of Aggressive Periodontitis (AgP) in Children; Susceptibility Patterns for Grade C Periodontitis in Young Individuals
Description
We’re looking for participants to help us learn more about a rare type of gum disease that affects young people.
Periodontitis is a gum disease that often runs in families, which suggests that genes may play a role. Scientists have looked at certain genes before, but no one has used a method called exome sequencing to study several affected families at once. This approach could help us find rare genetic changes that may be linked to the disease.
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
Children ages 12-25 Diagnosed with Severe Gum Disease (C/MIP)
Diagnosed between ages 12–25 (you can be older now)
Signs include deep gum pockets, bleeding, and bone loss around molars or front teeth
Brothers or Sisters of Someone who is at least 5 years old with C/MIP
Healthy Volunteers ages 12-25 Without Severe Gum Disease
No gum disease
Age, sex, and race matched
No deep pockets, bone loss, or major gum bleeding
Age Group: Adults
Principal Investigator: Renato Casarin

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