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Clinical Trial for People with Kidney Disease and High Blood Pressure
Protocol: STUDY00008250
Full Title
A Phase III, Randomised, Double -Blind, Active-controlled Study to Assess the Efficacy, Safety and Tolerability of Baxdrostat in Combination with Dapagliflozin Compared with Dapagliflozin Alone on Chronic Kidney Disease (CKD) Progression in Participants with CKD and High Blood Pressure
Description
The University at Buffalo (UB) Department of Medicine is looking for adults diagnosed with chronic kidney disease and high blood pressure for a clinical trial. The goal of the study is to investigate the safety and effectiveness of a new drug combination (baxdrostat/dapagliflozin) in treating kidney disease and high blood pressure.

Participants will be enrolled in the study for about 28 months and will complete 15 in-person study visits to the UB Clinical Research Office (located at 875 Ellicott Street in Buffalo). All participants will take dapagliflozin and some participants will be randomly assigned (which happens by chance, like flipping a coin) to take the study drug (baxdrostat) while others will take a placebo (which looks like the study drug but does not contain any medicine). They will complete physical exams, scanning tests, urine/blood tests, and surveys at each study visit.

Participants will receive $112.50 for completing a screening visit to determine eligibility and $75 for completing each in-person study visit.
Compensation: Yes
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Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
Eligibility
-Adults 18 years or older
-Have been diagnosed with chronic kidney disease AND high blood pressure
-Speak English
Age Group: Adults
Principal Investigator: RABI YACOUB
ClinicalTrials.gov: Open Study
Contact(s)
SEVIE KANDEFER
sk293@buffalo.edu
+1 716-898-4038

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