Testing of anti-plaque agents in subject-specific, clinically-relevant, subgingival biofilm models
This study is recruiting volunteers for a dental study through the University at Buffalo (UB) Microbiome Center in the UB School of Dental Medicine. The study team is researching if they can make accurate copies of bacteria patterns in mouth plaque (the “stuff” that collects between gums and teeth). The results of the study will help dentists to better understand how gum disease develops and comes back over time.
The study team is enrolling volunteers with healthy mouths and with gum disease. Participation will include a Screening Visit, and if eligible, three study visits. The Screening Visit will take about 1 – 1.5 hours and will involve a mouth exam to see if any gum disease is present. Study Visit 1 will take about 2 hours and Study Visits 2 and 3 should be about 1 – 1.5 hours. The study team will collect spit, fluid between your teeth and gums, and plaque at all three visits. The study visits will take place at the UB Microbiome Center dental clinic on the UB South Campus (at the corner of Main and Bailey).
The objective of this study is to test the efficacy of antimicrobials currently under development by Sunstar (a company that focuses on oral health products) as anti biofilm agents. We will first develop clinically-relevant, and subject-specific biofilm models, which will then be used to test the efficacy of different antimicrobials. The study includes the following objectives:
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
1. At least 21 years old
2. Have at least sixteen (16) teeth
3. Not currently pregnant
4. Not currently wearing braces or orthodontic appliances
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the
contact information above or email email@example.com and someone will assist you.
Your information will be shared only with the research study team for recruitment purposes and designated CTSI personnel for project quality
assurance and will remain confidential. Your information will be stored indefinitely. Should you no longer want this information to be provided
in the aforementioned ways, please contact firstname.lastname@example.org.