Mind to Quit Trial: Comparing Two ehavioral Approaches to Quitting Smoking in Mental Health Settings
The purpose of this study is to learn more about the advantages and disadvantages of two brief quitting smoking approaches that could be cost-effective in assisting individuals who suffer from serious mental illness. The first approach is brief advice combined with the use of nicotine gum and patches. The second approach uses an app on your smartphone combined with the use of nicotine gum and patches.
Approximately 254 people will be recruited to be in this study at the University at Buffalo. This study will be mostly remote. The screening, baseline, and follow-up visits will all be done over Zoom video calling. Participants may be asked to meet in person to provide a breath sample later in the study.
This study will test the effectiveness of the Learn to Learn to Quit app as a tool for smoking cessation in people with serious mental illness. In a multi-site, two-arm, randomized controlled trial, 508 individuals with serious mental illness will be randomly assigned to one of two conditions. In the experimental condition, participants will receive brief advice and use the Learn to Quit app. In the comparator condition, participants will receive brief advice. Participants in both conditions will receive combined Nicotine Replacement Therapy (standard dosing of nicotine patch plus approximately a 5-10 weeks supply of nicotine gum). Study duration will be 6 months, with 3 follow-up appointments at 1-month, 3-month, and 6-months.
Compensation may include cash, checks, gift cards, debit cards, or incentives like gift baskets, technology items, or merchandise.
(1) Current DSM-5 diagnosis of schizophrenia, schizoaffective, bipolar, or recurring major depressive disorder;
(2) Functional impairment as indicated by a score of_2 or greater on the WHODAS 8 item version
(3) Smoker as indicated by smoking 5 cigarettes per day over the past 6 months;
(4) Desire to quit smoking as indicated by self-reported serious intention to quitting tobacco within the next 6 months;
(5) Age 18 and older;
(6) Willing and medically eligible to use nicotine replacement therapy;
(7) Currently receiving psychiatric treatment and intent to receive treatment for the duration of the study (therapy, medications, etc.).
Let us know how the study team can reach you. If you do not hear back within 2 business days, reach out to the study team directly at the
contact information above or email email@example.com and someone will assist you.
Your information will be shared only with the research study team for recruitment purposes and designated CTSI personnel for project quality
assurance and will remain confidential. Your information will be stored indefinitely. Should you no longer want this information to be provided
in the aforementioned ways, please contact firstname.lastname@example.org.