Search and volunteer to participate in these available studies at UB. Your participation in research doesn't just benefit you, it helps advance healthcare for our entire community.
This study is for people undergoing surgery for mitral regurgitation (MR). Mitral regurgitation is a condition when your heart’s mitral valve does not close tightly which causes blood to flow backwards in your heart. The purpose of this study is to learn how safe and effective one value repair system is (the PASCAL System, an investigational device) compared to another one (the MitraClip System). Read More
Eligibility:
Adults ages 18+.
Have severe degenerative mitral regurgitation, and are considered prohibitive risk for mitral valve surgery by your heart team.
This study enrolls people who have been diagnosed with Tricuspid Regurgitation (TR) and have Heart Failure symptoms which are not under control despite treatment with current available therapies. The purpose of this study is to compare a new investigational (experimental) device plus optimal drug therapy with optimal drug therapy alone. Read More
Eligibility:
Adults ages 18+
Diagnosed with moderate or greater Tricuspid Regurgitation/Insufficiency with Heart Failure symptoms
This study enrolls adults who have had a recent stroke or stroke symptoms. The purpose of this study is to compare how well the study drug (tenecteplase) works for people with stroke symptoms. Read More
Eligibility:
-Adults ages 18+.
-Have been diagnosed with a stroke or stroke symptoms.
-Please contact the research team for other eligibility criteria.
This study enrolls people who have had a stroke in the past 2 weeks. This research is being done to figure out whether treatment for sleep apnea in people who have had a stroke or transient ischemic attack (TIA or "mini stroke"), improves recovery from stroke and helps prevent future stroke, heart problems, and death. Read More
Eligibility:
Adults ages 18+.
Are at an inpatient at an enrolling site (Buffalo General Hospital or Gates Vascular Institute).
Have had an ischemic stroke or TIA within the past 14 days.
Use a CPAP machine.
This study enrolls adults who are hospitalized for acute ischemic stroke. The purpose of this study is to learn how safe and effective the pRESET Thrombectomy Device is for the treatment of this condition and for removing the blood clot. Read More
Eligibility:
Adults ages 18+.
Currently admitted to the hospital for an acute ischemic stroke that began in the last 8 hours.